2-(phenylmethylene)-1-(diaminoalkoxy) cycloalkanes and their pharmaceutical uses

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United States of America Patent

PATENT NO 4727074
SERIAL NO

06578286

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Abstract

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The invention relates to selected stereoisomers having the E, E or E, Z configuration and within the Formula (I) ##STR1## wherein N is 2-4, A is alkylene or 2 or 3 carbon atoms, R is phenyl or substituted phenyl and R.sup.1 and R.sup.2 are lower alkyl, or, together with the carbon to which attached, form a heterocyclic ring; and pharmaceutically acceptable acid addition salts thereof, a process for their preparation and pharmaceutical compositions comprising the same. The compounds of the general formula (I) can be used in therapy due to their narcosis potentiating, analgesic and antiarrhythmial effect.

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Patent Owner(s)

  • EGYT GYOGYSZERVEGYESZETI GYAR;EGYT GYOGYSZERVEGYESZETI GYAR 30-38, KERESZTURI UT, BUDAPEST, X., HUNGARY A HUNGARIAN COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Budai, Zoltan Budapest, HU 29 79
Grasser, Katalin Budapest, HU 15 52
Lay, nee Konya Aranka Budapest, HU 10 43
Mezei, Tibor Budapest, HU 47 80
Petocz, Lujza Budapest, HU 42 159
Szirt, nee Kiszelly Eniko Budapest, HU 15 51

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