Slow-release sodium fluoride tablet, method of making, and method of treatment of osteoporosis
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United States of America Patent
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Feb 23, 1988
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N/A
app pub date -
Mar 21, 1986
filing date -
Aug 11, 1983
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Expired
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Abstract
A novel use for a slow-release sodium fluoride preparation. Such slow-release sodium preparation is shown to provide a safe but effective level of fluoride in serum, optimal for the treatment of osteoporosis. It minimizes gastrointestinal side effects by limiting the amount of fluoride released in the stomach and it reduces rheumatic complications by avoiding toxic levels of fluoride in serum. The amount of fluoride absorbed is nevertheless sufficient to stimulate bone formation and prevent fractures. Thus, the maintenance of serum fluoride as encompassed in this invention, allows for a safe and effective treatment of osteoporosis.
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