Pharmaceutical compositions
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United States of America Patent
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Nov 10, 1987
Grant Date -
N/A
app pub date -
Feb 26, 1986
filing date -
Mar 1, 1985
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Pharmaceutical compositions comprising mixtures of a histamine H.sub.2 -receptor antagonist such as cimetidine or ranitidine and sodium polyacrylate in a specified range of ratios have been found to exhibit synergistic effects in an in vivo test model for anti-ulcer or mucosal-protecting agents. Pharmaceutical compositions comprising mixtures of a histamine H.sub.2 -receptor antagonist such as cimetidine or ranitidine and sodium polyacrylate in the range of ratios are described for use in the treatment of gastritis or of gastro-duodenal ulcers. In a modification in the mixtures the sodium polyacrylate may be replaced wholly or in part by potassium or ammonium polyacrylate.
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