Galenical formulation of toloxatone
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United States of America Patent
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Oct 13, 1987
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N/A
app pub date -
Jul 29, 1983
filing date -
Jul 29, 1983
priority date (Note) -
Expired
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Abstract
A new formulation for the oral administration of Toloxatone, an anti-depressant, contains 400 to 600 mg of Toloxatone per unit dose. Such a high Toloxatone content is possible due to the discovery that Toloxatone is competitive with Tyramine towards the A form of a monomine oxidase, and thus does not cause hypertensive crisis. The anti-depressant composition of this invention can therefore be administered to the patient even when Tyramine is present in the patient's system.
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