Aromatic derivatives of 13-azaprostanoic acid

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United States of America Patent

PATENT NO 4695647
SERIAL NO

06592074

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Abstract

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Novel substituted phenyl eicosanoid analogs having the formula: ##STR1## and their pharmaceutically acceptable esters and salts, wherein: R is H or OH; R.sub.1 is H or lower alkyl; X is --CH.sub.2 --CH.sub.2 -- or cis --CH.dbd.CH--; Y is --CH.sub.2 --, ##STR2## --O-- or --S--; n is 0 or 1; and .circle.A is (1) an eicosanoid nucleus (ring system), (2) a carbocyclic analog of an eicosanoid nucleus or (3) a heterocyclic analog of an eicosanoid nucleus wherein one of the carbons in a carbocyclic analog is replaced by O, S or N.

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Patent Owner(s)

Patent OwnerAddress
SOUTH CAROLINA MEDICAL UNIVERSITY OF171 ASHLEY AVE STROM THURMOND BLDG RM 105 CHARLESTON SC 29425

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eller, Thomas D Mt. Pleasant, SC 3 7
Halushka, Perry V Charleston, SC 7 35
Knapp, Daniel R Charleston, SC 6 19
Mais, Dale Goose Creek, SC 1 2

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