Process for the manufacture of iso-malto-oligosaccharide monovalent haptens
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United States of America Patent
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Jun 16, 1987
Grant Date -
N/A
app pub date -
Jun 11, 1985
filing date -
Jun 15, 1984
priority date (Note) -
Expired
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Abstract
Iso-malto-oligosaccharide monovalent haptens were prepared by adding an aqueous sucrose solution to an aqueous solution of D-glucose containing more than 300 mmol glucose per 1000 U .alpha.(1.fwdarw.6)-D-glucosyl transferase at 265 to 310 K and a pH value of from 4.5 to 8.0 and a molar ratio of sucrose to glucose of from 0.5 to 2.0. After consumption of the sucrose, glucose, liberated fructose and undesired oligosaccharides are separated in a known manner. The process of the invention allows a particularly economical preparation of the monovalent haptens which serve for the prophylaxis of undesired dextran induced anaphylactoid side effects (DIAR).
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