Hydroxamic acid and pharmaceutical preparations containing the same

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United States of America Patent

PATENT NO 4670469
SERIAL NO

06584532

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Hydroxamic acids, pharmaceutical preparations containing the same, new .omega.(2'-naphthoxy)-alkylhydroxamic acids as well as a process for their production are disclosed. The new compounds display antiasthmatic and further pharmacologically valuable characteristics. They are prepared by reacting the corresponding carboxylic acid ester or amide with hydroxylamine or its salt under the described conditions into compounds of Formula I, R--CO--NH--OH. The compounds of Formula I are useful in human and veterinary medicine as medicaments the active principal of which is the inhibition of lipoxygenase, thus as antiasthmatic, antianaphylactic, antiphlogistic, antirheumatic and antithrombotic preparations.

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Patent Owner(s)

Patent OwnerAddress
VEB FAHLBERG-LIST MAGDEBURG ALT SALBKE 60-63 3013 MAGDEBURG GERMANYNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Grupe, Renate Berlin, DD 2 17
Kuhn, Hartmut Berlin, DD 2 8
Lyr, Horst Eberswalde, DD 7 24
Rapoport, Samuel M Berlin, DD 2 17
Schewe, Tankred Berlin, DD 5 28
Slapke, Jurgen Berlin, DD 2 4
Strumpf, Thomas Potsdamm, DD 4 7
Zanke, Dieter Potsdamm, DD 6 9

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