Process for the preparation of L-.alpha.-aminoacids
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United States of America Patent
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May 19, 1987
Grant Date -
N/A
app pub date -
Jan 31, 1985
filing date -
Feb 2, 1984
priority date (Note) -
Expired
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Abstract
The process of the invention is useful for the preparation of L-.alpha.-aminoacids and is based on the use of an N-carbamyl-.alpha.-aminoacid compound which is contacted with a E.C.3.5.2.2, a dihydropyrimidine hydrolase, enzyme to form a D-hydantoin. The D-hydantoin is hydrolyzed and racemized to form the D-N-carbamyl-.alpha.-aminoacid and the L-N-carbonyl-.alpha.-aminoacid. The L-N-carbamyl-.alpha.-aminoacid is thereafter transformed into the corresponding L-.alpha.-aminoacid.
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