1-fluoro, 4-fluoro, and 1,4-difluoro-2'-halo anthracycline antibiotics
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United States of America Patent
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May 5, 1987
Grant Date -
N/A
app pub date -
Mar 20, 1985
filing date -
Mar 20, 1985
priority date (Note) -
Expired
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Abstract
Anthracycline antibiotics represented by the formula (I) ##STR1## wherein R is hydrogen or hydroxyl, one of X and Y is fluorine and the other is hydrogen or both X and Y are fluorine, and S is a 2-halo sugar moiety; pharmaceutical preparations containing the same; and a method for inhibiting the growth of mammalian tumors are disclosed.
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