Process of using improved silica-based chromatographic supports containing additives

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United States of America Patent

PATENT NO 4648975
SERIAL NO

06833263

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Abstract

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Silica-based chromatographic and reactive materials are disclosed with surfaces modified to contain or to be coated with oxides, hydrous oxides, hydroxides, carbonates or silicates of aluminum, iron, or other suitable metals such as zirconium or titanium. The materials exhibit good resistance to dissolution and resulting loss of activity or clogging. This good resistance is particularly evident even in the high pH region (above 8-9) and in the high temperature region (above 35.degree. C.) where the dissolution rates and solubilities of aluminosilicates and of trivalent iron oxides are much smaller than those of silica.

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Patent Owner(s)

Patent OwnerAddress
MACEDO PEDRO B6100 HIGHBORO DRIVE BETHESDA MD 20817
LITOVITZ THEODORE A3022 FRIENDS ROAD ANNAPOLIS MD 21401

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barkatt, Aaron 6100 Highboro Dr., Silver Spring, MD 13 189
Macedo, Pedro B 6100 Highboro Dr., Bethesda, MD 20817 32 673

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