Modified protease inhibitors, process for their preparation, and pharmaceutical compositions prepared therefrom

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United States of America Patent

PATENT NO 4636489
SERIAL NO

06628355

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Abstract

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The invention relates to novel, modified eglins B and C, to the preparation thereof, and to pharmaceutical compositions which contain these compounds. Compared with eglin B and C, the modification consists in a terminal shortening. The compounds of the invention can be prepared e.g. by limited enzymatic proteolysis of elgins or by peptide synthesis.

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Patent Owner(s)

Patent OwnerAddress
UCP GEN-PHARMA AGTALSTRASSE 82 CH-4001 ZURICH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dodt, Johannes Munich, DE 6 90
Fritz, Hans Hohenbrunn, DE 27 224
Seemuller, Ursula Munich, DE 8 102

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