Angiotensin-converting enzyme inhibiting dipeptide derivatives
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United States of America Patent
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Oct 14, 1986
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N/A
app pub date -
May 14, 1982
filing date -
May 14, 1982
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Expired
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Abstract
Dipeptides having the formula ##STR1## wherein A is halogen, hydrogen, lower alkyl, or lower alkoxy; B is hydrogen or lower alkyl, or A and B are taken together to form an ortho-methylene or ethylene bridge; R is hydrogen, lower alkyl, or phenylalkyl; and X.sup.1 and X.sup.2 are independently chosen from hydroxy or lower alkoxy; are inhibitors of angiotensin-converting enzyme and can be used for the treatment of hypertension in mammals.
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