Silicon-bearing amides
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United States of America Patent
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Sep 9, 1986
Issued Date -
N/A
app pub date -
Aug 25, 1983
filing date -
Sep 10, 1979
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Compounds of the formula I: ##STR1## wherein each of R.sup.1, R.sup.2 and R.sup.3 is, independently, (a) alkyl having from 1 to 22 carbon atoms; or (b) of the formula ##STR2## in which m is 0, 1 or 2, and each of R' and R' is independently a hydrogen atom, alkyl having from 1 to 3 carbon atoms, alkoxy having from 1 to 3 carbon atoms, or halo having an atomic weight of from about 19 to 127; and R is of an aralkyl-, phenyl- tryptophanyl- or benzocycloalkyl-type, are obtained by hydrogenating corresponding .alpha.-.beta. ethylenically-unsaturated analogs (II), which in turn are obtained by hydrogenating corresponding .alpha.-.beta. acetylenically-unsaturated analogs. Compounds I and II are useful as anti-atheroslerotic agents.
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- 2 Citation Count
- C07F Class
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- 39 Age