Method for the production of therapeutically administrable plasma derivatives filled in final containers
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United States of America Patent
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Aug 26, 1986
Grant Date -
N/A
app pub date -
Mar 7, 1984
filing date -
Mar 16, 1983
priority date (Note) -
Expired
status (Latency Note)
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Abstract
There is disclosed a method for the production of therapeutically administrable plasma derivatives filled in final containers, which are free of prekallikrein activator, hypotensively active constituents and other undesired pharmacologically active substances, of plasma or plasma crude fractions by stepwise enrichment of the plasma proteins, sterile filtration and optionally virus inactivation. In order to make available such plasma fractions that do not develop pharmacologically negative side effects when applied and are producible with an improved activity and yield, C.sub.1 -esterase inhibitor is added during the production process of the plasma derivative, yet prior to its filling into final containers.
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