Method for quantitatively assaying blood coagulation factor XII in human plasma
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United States of America Patent
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Jul 1, 1986
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N/A
app pub date -
Oct 28, 1982
filing date -
Nov 2, 1981
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Expired
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Abstract
A method for assaying blood coagulation factor XII in human blood plasma wherein plasma is treated with an activator in order to convert factor XII present in the plasma into factor XIIa, the latter is reacted with a tripeptide derivative which is split by the enzymatic action of factor XIIa and forms a colored or fluorescent split product, and the quantity of this split product is measured photometrically, spectrophotometrically or fluorescence-spectrophotometrically.
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