Azulene derivatives, processes of their synthesis and their uses as anti-ulcerative and anti-inflammatory agents
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United States of America Patent
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Jun 17, 1986
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N/A
app pub date -
Aug 17, 1984
filing date -
Aug 24, 1983
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Expired
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Abstract
A new series of azulene derivatives are disclosed. These compounds are stable to light and heat and are useful as anti-ulcerative and anti-inflammatory agents. Such compounds can be synthesized by reacting 2H-cyclohepta(b) furan-2-one or its derivative substituted by a lower alkyl with a suitable enamine derived from a corresponding aldehyde or ketone, and then sulfonating the compound resulting from said reaction.
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