Processes for the preparation of liposome drug delivery systems
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United States of America Patent
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Nov 5, 1985
Issued Date -
N/A
app pub date -
Sep 7, 1984
filing date -
Aug 16, 1982
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Expired
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Abstract
Process and apparatus for the production of medicament containing liposomes, comprising an aliphatic lipid-sterol-water lamellae, wherein a clear, mixed micellar medicament-detergent-aliphatic lipid-sterol sample is applied to a gel filtration column. The column effluent is continuously monitored to detect the liposome fraction eluted, which is collected. The free medicament, detergent, lipid and/or sterol may be recirculated back to the column.
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