Pharmaceutical combination composition and associated method
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United States of America Patent
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Oct 15, 1985
Issued Date -
N/A
app pub date -
Feb 17, 1984
filing date -
Jan 6, 1983
priority date (Note) -
Expired
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Abstract
A novel combination pharmaceutical composition is described, together with a method for making the same, wherein the pharmaceutcially active ingredients are separately milled and then formed into separate granules, and only thereafter blended together to form the combination composition. The method for achieving this novel combination composition is also described. In particular, a novel combination composition of triamterene and hydrochlorothiazide having improved bioavialability and novel effectiveness to prevent or eliminate hypokalemic side effects is also described.
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