Antihypertensive substituted imidazole derivatives
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United States of America Patent
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Oct 1, 1985
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N/A
app pub date -
Jul 7, 1982
filing date -
Jul 10, 1981
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Expired
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Abstract
The invention provides novel compounds of the formula: ##STR1## wherein the various substituents are defined herein below. Processes for the preparation of these compounds are described, as are novel pharmaceutical compositions comprising at least one of the compounds of their salts. The compounds and their non-toxic salts exhibit valuable pharmacological activity and are useful in the treatment of mammals, especially as antihypertensive agents. Furthermore, some of the compounds have proved to possess antithrombotic and diuretic activity. Antimycotic and antifungal properties have also been found.
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