Substance TH69E and immunopotentiator containing the same

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United States of America Patent

PATENT NO 4543259
SERIAL NO

06352068

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Abstract

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A substance TH69E having the following characteristics: (a) elementary analysis: C: 24.25%, H: 4.46% and N: 6.55%; (b) molecular weight: about 60,000.+-.15,000 (Biogel P-Series Column); (c) color: white amorphous powder; (d) decomposition point: 180.degree. C. (as determined by a capillary method with use of Silicone Oil WF-30--the color changes to brown); (e) ultraviolet absorption spectrum: as shown in FIG. 1 of the drawings; (f) infrared absorption spectrum: as shown in FIG. 2 of the drawings; (g) pH: 6.7 to 7.1 in an aqueous solution; (h) solubility: soluble in water, and insoluble in ethanol, acetone, n-hexane, n-butanol and phenol; and (i) color reactions: phenol-sulfuric acid reaction, anthrone reaction, Molisch reaction, orcinol-hydrochloric acid reaction, Ninhydrin reaction being positive, and Elson-Morgan's reaction being negative. The substance TH69E exhibits immunopotentiating activities such as a collagen decomposition enhancing effect, an infection preventive effect and an interferon inducing effect.

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Patent Owner(s)

Patent OwnerAddress
TERU HOSHINO4-16 CHIYODA-MACHI SEDAI-SHI MIYAGI-KEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abe, Nobuyuki Sendai, JP 22 121
Hoshino, Fumihiko Sendai, JP 9 34
Hoshino, Tadahiko Sendai, JP 1 0
Katzukura, Yoshiteru Sendai, JP 1 0
Kuroda, Yoko Sendai, JP 2 4
Utsumi, Yoko Izumi, JP 1 0
Watabe, Nobuyuki Izumi, JP 4 31
Yamaguchi, Takahiro Sendai, JP 464 4091

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