Compound having vasodilating, antiaggregating and hypocholesterolemic activities, process for the preparation thereof and pharmaceutical compositions therefrom
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United States of America Patent
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Sep 17, 1985
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N/A
app pub date -
Oct 7, 1983
filing date -
Oct 15, 1982
priority date (Note) -
Expired
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Abstract
The compound having formula (I) ##STR1## is obtained by reacting 1,2-diphenyl-4-[2-phenylsulfinyl)-ethyl]-4-hydroxymethyl-pyrazolidine-3,5-dione (hydroxymethylsulfinpyrazone) with nicotinic acid, in the presence of activating agents such as DCCD. (I) is endowed with marked vasodilating, antiaggregating and hypocholesterolemic properties.
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