N-acetamilide, N-(phenoxy-2-propanol)- and N-(phenylamino-2-propanol)-cyclicamines

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United States of America Patent

PATENT NO 4530923
SERIAL NO

06435493

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to new cyclic imines of the general formula (I), ##STR1## wherein A represents carbonyl or hydroxymethylene, B is oxygen or imino, R stands for hydrogen or lower alkyl, X.sub.1 and X.sub.2 may be the same or different and represent hydrogen, halogen, lower alkyl or alkoxy, amino or nitro, n is 6 or 7, and m is 0 or 1, and pharmaceutically acceptable acid addition salts and quaternary salts thereof. The invention relates further to a process for the preparation of said compounds, to pharmaceutical compositions containing said compounds as the active ingredient and to a process for the preparation of said pharmaceutical compositions. The cyclic imine derivatives of the invention possess valuable antiarrhythmic properties and can be used to advantage in the treatment of cardiovascular diseases.

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Patent Owner(s)

Patent OwnerAddress
EGYT GYOGYSZERVEGESZETI GYARKERESZTURI U 30-38 BUDAPEST

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berenyi, nee Poldermann Edit Budapest, HU 7 48
Fekete, Bela Budapest, HU 1 0
Keszthelyi, nee Udvary Eva Szeged, HU 1 0
Papp, Gyula Szeged, HU 7 50
Rakoczi, Jozsef Budapest, HU 4 58
Szekeres, Laszlo Szeged, HU 6 68

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