Human leukemia virus-related peptides, antibodies of the peptides and a process for production of the antibodies

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United States of America Patent

PATENT NO 4525300
SERIAL NO

06535115

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Abstract

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An antibody of a human leukemia virus-related peptide obtained by collecting an antibody produced in a mammal body by administering to the mammal an antigen prepared by reacting a human leukemia virus-related peptide selected from the group consisting of: (a) a peptide represented by formula (1): H-Tyr-Val-Glu-Pro-Thr-Ala-Pro-Gln-Val-Leu-H (1) (b) a peptide represented by formula (2): R-Ile-Pro-His-Pro-Lys-Asn-Ser-Ile-Gly-Gly-Glu-Val-OH (2) wherein R is the same as drefined above; (c) a peptide represented by formula (3): R-Thr-Trp-Thr-Pro-Lys-Asp-Lys-Thr-Lys-Val-Leu-OH (3) wherein R is the same as defined above; (d) a peptide represented by formula (4): H-Val-Val-Gln-Pro-Lys-Lys-Pro-Pro-Pro-Tyr-OH (4) (e) a peptide represented by formula (5): R-Met-Gly-Gln-Ile-Phe-Ser-Arg-Ser-Ala-Ser-Pro-OH (5) wherein R is the same as defined above; and (f) a peptide represented by formula (6): H-Tyr-Pro-Glu-Gly-Thr-Pro-Lys-Asp-Pro-Ile-Leu-Arg-Ser-Leu-OH (6) as a hapten, with a carrier in the presence of a hapten-carrier binding agent.

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Patent Owner(s)

Patent OwnerAddress
OTSUKA PHARMACEUTICAL CO LTDTOKYO
JAPANESE FOUNDATION OF CANCER RESEARCH10-6-3-CHOME ARIAKE KOTO-TU TOKYO 135

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Imagawa, Kenichi Tokushima, JP 18 139
Shimizu, Fumio Tokushima, JP 55 985
Sugano, Haruo Tokyo, JP 20 281
Yoshida, Mitsuaki Tokyo, JP 20 242

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