Collagen-thrombin compositions
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United States of America Patent
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May 7, 1985
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N/A
app pub date -
Nov 16, 1983
filing date -
Nov 16, 1983
priority date (Note) -
Expired
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Abstract
A method of forming a collagen-thrombin hemostatic composition is comprised of forming a homogeneous aqueous admixture of collagen and thrombin at a basic pH and lyophilizing the collagen-thrombin admixture to form a stable collagen sponge having thrombin therein. The collagen utilized in the process is absorbable when placed in vivo. Additionally, a lyophilized collagen product is comprised of collagen which is absorbable when placed in vivo and thrombin distributed within the collagen. The collagen product is storage stable.
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