Method of producing an antithrombin III-heparin concentrate or antithrombin III-heparinoid concentrate
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United States of America Patent
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Apr 9, 1985
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N/A
app pub date -
May 18, 1984
filing date -
May 20, 1983
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Expired
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Abstract
In a method of producing an antithrombin III-heparin or an antithrombin III-heparinoid concentrate, heparin or heparinoid is added to human plasma or to antithrombin III containing plasma fractions to form an antithrombin III-heparin or antithrombin III-heparinoid complex, the complex thus formed is adsorbed on an anion exchanger, and eluted with a salt solution; then the antithrombin III-heparin or antithrombin III-heparinoid complex contained in the eluate is separated from salts and undesired proteins, and the resulting product is loyphilized.
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