Omega cycloalkyl prostaglandins
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United States of America Patent
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Feb 12, 1985
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N/A
app pub date -
Nov 14, 1983
filing date -
Nov 14, 1983
priority date (Note) -
Expired
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Abstract
This invention encompasses prostaglandins of the formula I ##STR1## wherein R'' represents hydroxymethyl, hydroxyacetyl or --CO.sub.2 R'' wherein R'' represents hydrogen or lower alkyl containing 1 to 6 carbon atoms; R' represents lower alkyl containing 1 to 6 carbon atoms, vinyl or ethynyl; R' represents cycloalkyl containing 3 to 5 carbon atoms; and the wavy line represents optional R,S stereochemistry. These compounds are potent antisecretory compounds and cytoprotective agents with reduced diarrhea side effects.
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