1,2,3,4,4a,9b-Hexahydro-4a-piperazinylmethyl-4-dibenzofuranone or -dibenzofuranol derivatives
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United States of America Patent
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Oct 11, 1983
Grant Date -
N/A
app pub date -
Jun 9, 1982
filing date -
Jun 12, 1981
priority date (Note) -
Expired
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Abstract
The present invention is dealing with compounds of the formula: ##STR1## and pharmaceutically acceptable salts thereof, in which R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are identical or different and represent hydrogen, halogen, lower alkyl or alkoxy or trifluoromethyl; R.sub.5 represents hydrogen or lower alkyl, X represents hydrogen and Y represents hydroxy, or X and Y together represent oxygen and Ar represents an optionally substituted aromatic moiety, having potent anti-bronchoconstrictor properties.
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