1(2H)-Isoquinolone compounds and acid addition salts thereof

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United States of America Patent

PATENT NO 4393210
SERIAL NO

06182188

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Abstract

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1(2H)-Isoquinolone compounds represented by the formula (1) ##STR1## wherein Y represents hydrogen, chlorine or a methoxy group, Z represents a straight chain or branched chain divalent saturated aliphatic hydrocarbon group having 2 to 4 carbon atoms, R.sub.1 represents a cyano group, a lower alkoxycarbonyl group, a carbamoyl group, an N-substituted carbamoyl group, a phenyl group or a substituted phenyl group, R.sub.2 represents hydrogen or a lower alkyl group, and R.sub.3 represents a lower alkyl group, or R.sub.2 and R.sub.3 can form, when taken together with the nitrogen atom to which they are attached, a heterocyclic group, and the acid addition salts thereof, useful as analgesic, gastric secretion inhibitory, anti-depression, anti-histamine, anti-cholinergic and anti-ulcer agents.

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Patent Owner(s)

Patent OwnerAddress
TAIHO PHARMACEUTICAL CO LTDTOKYO 101-0054
MARUKO SEIYAKU CO LTDNO 5-17 KODAMA 1-CHOME NISHI-KU NAGOYA-SHI AICHI

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fujiwara, Khosuke Tokushima, JP 2 3
Katho, Eiichi Aza-nishimachi, JP 2 3
Miyake, Hidekazu Tokushima, JP 85 528
Ohtani, Osamu Minokamo, JP 14 126
Senda, Shigeo Gifu, JP 2 3

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