Process of producing a peptide antibiotic with Bacillus circulans

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United States of America Patent

PATENT NO 4360593
SERIAL NO

06346451

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Abstract

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A novel peptide antibiotic complex designated herein as Bu-2470 is produced by fermentation of Bacillus circulans strain G493-B6 (ATCC 31,805). Complex Bu-2470 may be separated into four bioactive peptide antibiotics designated as Bu-2470A, B.sub.1, B.sub.2a, and B.sub.2b. The complex and individual bioactive factors possess significant antimicrobial activity.

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Patent Owner(s)

Patent OwnerAddress
BRISTOL-MYERS COMPANYNEW YORK NEW YORK 10154

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kawaguchi, Hiroshi Tokyo, JP 268 3529
Konishi, Masataka Yokohama, JP 74 361
Miyaki, Takeo Yokohama, JP 34 163
Tsukiura, Hiroshi Mitaka, JP 6 12

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