Method for treating tumors using cis-diammineplatinum (II) organophosphate complexes
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United States of America Patent
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Sep 22, 1981
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N/A
app pub date -
Dec 26, 1979
filing date -
Mar 7, 1979
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Expired
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Abstract
Cis-diammineplatinum (II) organophosphate complexes where the organophosphate moiety is a glycerophosphate or a monosaccharide phosphate moiety are prepared by reaction of cis-diaquodiammineplatinum (II) salts with alkali metal organophosphates. The resulting complexes possess pronounced anti-tumor activity and low toxicity; consequently, they have high therapeutic indices.
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