Process for the isolation of ergot alkaloids from culture suspensions
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United States of America Patent
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Dec 2, 1980
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N/A
app pub date -
Dec 20, 1978
filing date -
Dec 20, 1977
priority date (Note) -
Expired
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Abstract
A process for isolating ergot alkaloids from culture suspensions, in which after mechanical filtration, the residue is dried in a fluidized drying bed and the alkaloids are extracted with an aprotic organic solvent, reextracted with a weakly acidic aqueous solution which is subsequently made basic, and finally extracted with a water-immiscible organic solvent, from which the alkaloids are isolated in a conventional manner. In certain instances, the culture suspension is stirred with an adsorbent clay to entrain the water-soluble alkaloids.
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