Activated matrix and method of activation
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United States of America Patent
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Sep 23, 1980
Grant Date -
N/A
app pub date -
Feb 2, 1978
filing date -
Feb 8, 1977
priority date (Note) -
Expired
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Abstract
Carbonylation of a polysaccharide and the product of that carbonylation. The carbonylated product can be used to prepare an affinity chromatography matrix which is an uncharged species of varying pH's. The carbonylated product is also useful for the preparation of other compounds. Typical polysaccharides are agarose, starch, dextran, cellulose and regenerated cellulose and typical carbonylating agents are N,N'-carbonyl diimidazole; N,N' carbonyl di-1,2,3-benzotriazole; and N,N'-carbonyl di-1,2,4-triazole.
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