Chemical compounds
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United States of America Patent
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Mar 18, 1980
Issued Date -
N/A
app pub date -
Aug 12, 1976
filing date -
Jul 31, 1970
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Novel semisynthetic .beta.-lactam intermediates of use in the production of cephalosporins, penicillins and related .beta.-lactam antibiotic compounds are provided. The novel compounds are prepared from .beta.-lactams obtained by cleavage of the 1,2-sulphur-carbon bond of a penicillin 1-oxide (with subsequent internal or external trapping of the sulphur atom to leave a residual substituent as the .beta.-lactam nitrogen) by removal of the said residual substituent by an oxidative cleavage reaction.
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