BIOTIN-STREPTAVIDIN CLEAVAGE COMPOSITION AND LIBRARY FRAGMENT CLEAVAGE
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United States of America
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Apr 10, 2025
app pub date -
Nov 14, 2024
filing date -
Nov 14, 2024
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Abstract
An example of a biotin-streptavidin cleavage composition includes a formamide reagent and a salt buffer. The formamide reagent is present in the biotin-streptavidin cleavage composition in an amount ranging from about 10% to about 50%, based on a total volume of the biotin-streptavidin cleavage composition. The salt buffer makes up the balance of the biotin-streptavidin cleavage composition. In some examples, the biotin-streptavidin cleavage composition is used to cleave library fragments from a solid support. In other examples, other mechanisms are used to cleave library fragments from a solid support.
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