HANGTAIMYCIN DERIVATIVES AND THEIR PREPARATION METHODS AND APPLICATION
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United States of America
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Apr 10, 2025
app pub date -
Nov 22, 2024
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Nov 22, 2024
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The embodiment of the present invention discloses Hangtaimycin derivatives and their preparation and application. Hangtaimycin derivatives are obtained by fermentation of Streptomyces spectabilis CCTCC M2017417 and its genetically knockout mutant strain in SFMR medium, with further isolation, purification, and alcoholysis. Through screening, Hangtaimycin derivatives showed excellent anti-inflammatory and analgesic, anti-tumor, liver injury protection, cell membrane protection, and drug addiction prevention activities, providing new drug leads for developing related drugs.
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