DIARYL COMPOUND AS TUBULIN/SRC DUAL TARGET INHIBITOR

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United States of America

APP PUB NO 20250115613A1
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18728577

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Abstract

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The present invention provides a diaryl compound as a tubulin/Src dual target inhibitor. The present invention also provides a diaryl compound represented by formula I, a tautomer, a stereoisomer, a solvate, a pharmaceutically acceptable salt, or a prodrug thereof. The diaryl compound can be used as a dual target inhibitor against tubulin and Src kinase and can also be used as a mono-target inhibitor against tubulin or Src kinase. The compound of the present invention can significantly inhibit the polymerization of tubulin monomers and cell proliferation.

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Patent Owner(s)

Patent OwnerAddress
WUHAN HUMANWELL INNOVATIVE DRUG RESEARCH AND DEVELOPMENT CENTER LIMITED COMPANYROOM 705-2 BUILDING C7 NO 666 GAOXIN ROAD WUHAN EAST LAKE HI-TECH DEVELOPMENT ZONE WUHAN HUBEI 430075

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
LEI, Sijun Wuhan, Hubei, CN 37 48
LI, Li'e Wuhan, Hubei, CN 9 8
LIU, Lifei Wuhan, Hubei, CN 6 3
WEI, Wenjun Wuhan, Hubei, CN 5 85
WU, Zhiqiang Wuhan, Hubei, CN 362 5279
YANG, Hui Wuhan, Hubei, CN 265 893
YANG, Jun Wuhan, Hubei, CN 792 8454
ZANG, Yang Wuhan, Hubei, CN 7 2
ZHANG, Xin Wuhan, Hubei, CN 895 4200
ZHANG, Xuejun Wuhan, Hubei, CN 70 708

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