MASKED IL12 PROTEIN
Number of patents in Portfolio can not be more than 2000
United States of America
Stats
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N/A
Issued Date -
Apr 10, 2025
app pub date -
Feb 15, 2023
filing date -
Feb 15, 2023
priority date (Note) -
Published
status (Latency Note)
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Importance

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Abstract
Disclosed herein are masked IL12 proteins that can be activated both in vitro and in vivo. Surprisingly, a small, bioorthogonal group is sufficient to deactivate or mask the IL12 protein, which can thereafter be activated by contacting the masked IL12 protein with the bioorthogonal reactive partner of the Trigger joining the IL12 protein to the mask (either a dienophile or a diene). The invention also relates to methods for using and preparing said masked IL12 proteins.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
TAGWORKS PHARMACEUTICALS B V | 6525 ED NIJMEGEN |
International Classification(s)

- 2023 Application Filing Year
- A61K Class
- 11803 Applications Filed
- 2060 Patents Issued To-Date
- 17.46 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
DE, ROODE Kim Elisa | Nijmegen, NL | 1 | 0 |
# of filed Patents : 1 Total Citations : 0 | |||
DEN, BROK Martijn Hendrikus Martinus Gerardus Maria | Nijmegen, NL | 1 | 0 |
# of filed Patents : 1 Total Citations : 0 | |||
KLEIJN, Laurens Henri Johan | Pittsburgh, US | 4 | 0 |
# of filed Patents : 4 Total Citations : 0 | |||
ROBILLARD, Marc Stefan | Eindhoven, NL | 32 | 245 |
# of filed Patents : 32 Total Citations : 245 | |||
ROSSIN, Raffaella | Eindhoven, NL | 23 | 163 |
# of filed Patents : 23 Total Citations : 163 | |||
VERSTEEGEN, Ronny Mathieu | Hegelsom, NL | 23 | 154 |
# of filed Patents : 23 Total Citations : 154 | |||
WOUTERS, Lieke Willemijn Maria | Nijmegen, NL | 1 | 0 |
# of filed Patents : 1 Total Citations : 0 | |||
ZIJLMANS, Lucas Hendricus Maria | Lent, NL | 1 | 0 |
# of filed Patents : 1 Total Citations : 0 |
Cited Art Landscape
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Patent Citation Ranking
- 0 Citation Count
- A61K Class
- 0 % this patent is cited more than
- < 1 Age
Forward Cite Landscape
- No Forward Cites to Display

Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
---|---|---|---|---|
3.5 Year Payment | $1600.00 | $800.00 | $400.00 | Oct 10, 2028 |
7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Oct 10, 2032 |
11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Oct 10, 2036 |
Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge - 3.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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