MODIFIED IMMUNE CELLS AND METHODS FOR USE THEREOF

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20250114454A1
SERIAL NO

18931863

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The disclosure features compositions containing chimeric antigen receptor (CAR) immune cells that have been modified to reduce and/or eliminate expression or activity of a natural killer cell lectin A (NKG2A) polypeptide and/or a cluster of differentiation 94 (CD94) polypeptide, and methods for use thereof to treat a neoplasia.

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Patent Owner(s)

Patent OwnerAddress
THE BROAD INSTITUTE INC415 MAIN STREET CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Manguso, Robert Boston, US 10 8
Yates, Kathleen Cambridge, US 4 0

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