COMPOUND, COMPOSITION AND METHODS FOR LOWERING CIRCULATING GLUCOSE
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United States of America
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Apr 10, 2025
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Oct 10, 2023
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Oct 10, 2023
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Abstract
The present invention provides a compound or derivatives thereof capable of lowering circulating glucose in a subject. The compound is a recombinant placenta-specific protein 9 (Plac9) or derivatives thereof that can enhance glucose uptake by liver cells or hepatocytes in an insulin-independent manner, thereby lowering the circulating glucose. The present invention also provides a composition including an effective amount of the compound or derivatives thereof and a method for treating diseases or conditions associated with or arising from high circulating glucose such as diabetes mellitus.
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