CONCURRENT TARGETING OF ONCOGENIC PATHWAYS TO ENHANCE CHEMOTHERAPY AND IMMUNOTHERAPY

United States of America

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Apr 10, 2025
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Aug 1, 2022
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Aug 1, 2022

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Abstract

The present invention relates to the field of cancer. More specifically, the present invention provides compositions and methods for treating cancer by targeting YAP1 and STAT3 pathways. In a specific embodiment, the present invention provides a method for increasing sensitivity of cancer in a subject to chemotherapy and/or immunotherapy comprising the step of administering to the subject an effective amount of a YAP1 inhibitor and a STAT3 inhibitor.

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UNIV JOHNS HOPKINS	3400 NORTH CHARLES STREET BALTIMORE MARYLAND 21218 US

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Inventor Name	Address	# of filed Patents	Total Citations
Hoque, Mohammad O	Towson, US	7	2
Sadhukhan, Pritam	Baltimore, US	2	4

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CONCURRENT TARGETING OF ONCOGENIC PATHWAYS TO ENHANCE CHEMOTHERAPY AND IMMUNOTHERAPY

Number of patents in Portfolio can not be more than 2000

United States of America

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18293456

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