BRAIN-METASTATIC LUNG CANCER CELL LINE AND USE OF NOGGIN AS MARKER FOR BRAIN METASTASIS OF LUNG CANCER
Number of patents in Portfolio can not be more than 2000
United States of America
Stats
-
N/A
Issued Date -
Apr 10, 2025
app pub date -
Oct 4, 2024
filing date -
Oct 4, 2024
priority date (Note) -
Published
status (Latency Note)
Importance
Abstract
The present invention relates to a brain-metastatic lung cancer cell line and a use of Noggin as a marker for brain metastasis of lung cancer. In the present invention, a brain metastatic lung cancer cell line with optimized characteristics for brain metastasis was established by repeatedly transplanting the lung cancer cell line through the carotid artery. In addition, in the brain metastatic lung cancer cell line, the expressions of Noggin protein and its mRNA are reduced, confirming that the motility and invasiveness of cells are reduced and adhesion increased. Therefore, the Noggin protein or its gene is expected to be useful as a biomarker for diagnosis of brain metastasis of lung cancer and its target therapy.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully