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Abstract

The present disclosure provides a cryo-electron microscopy image processing method and apparatus, a terminal, and a storage medium. The cryo-electron microscopy image processing method includes: obtaining a cryo-electron microscopy image; encoding the cryo-electron microscopy image into latent variables through an encoder; converting the latent variables into an atomic model structure through a decoder; correcting the atomic model structure using a loss function to obtain a corrected atomic model structure, where the loss function includes a bond length constraint loss function, a clash constraint loss function, and a spring constraint loss function; and converting, through a projector module, the corrected atomic model structure into a density map represented by Gaussian spheres, and projecting the density map to obtain a projection image.

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First Claim