SPECIMEN EMBEDDING
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United States of America
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Issued Date -
Apr 3, 2025
app pub date -
Sep 25, 2024
filing date -
Sep 25, 2024
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Abstract
Embedding compositions with light-attenuating properties for preparing specimens for sectioning and imaging are disclosed. An embedding composition may be a colloidal suspension including a continuous phase such as optimal cutting temperature compound (OCT), paraffin, or epoxy, etc., and a dispersed phase such as carbon powder, red blood cells, or barium sulfate, etc. The dispersed phase may reduce the transmission and/or scattering of light within the embedding composition, resulting in reduction or elimination of artifacts such as edge brightening, glow, and/or blurring. In some cases, the light-attenuation properties of an embedding composition may be adjusted to approximate or match those of the specimen.
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