Personalized Medicine Platform to Dissect Brain Tumor Microenvironment and Rapidly Test Therapeutic Efficacy
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United States of America
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Apr 3, 2025
app pub date -
Sep 30, 2024
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Sep 30, 2024
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Abstract
A device for modeling a brain tumor microenvironment and testing therapeutic efficacy is provided. The device includes a vascular tissue model and an ultrasound device that is capable of delivering focused ultrasound insonation. The vascular tissue model includes a rigid 3D printed scaffold. The scaffold includes one or more scaffold microfluidic channels, two or more inlets, and a central chamber. The central chamber contains a hydrogel or other biocompatible scaffolds. The hydrogel includes one or more hydrogel microfluidic channels as well as living cells.
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