CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS
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United States of America
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Issued Date -
Apr 3, 2025
app pub date -
Nov 21, 2024
filing date -
Nov 21, 2024
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Abstract
The subject matter described herein is directed to ferroportin inhibitor compounds of Formula I or I′ and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds, and methods of administering the compounds for prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, particularly iron overload states, such as thalassemia, sickle cell disease and hemochromatosis, and also kidney injuries.
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