DOUBLE-CROSSLINKED FIBRIN GEL, RAW MATERIAL COMPOSITION AND KIT THEREOF, AND APPLICATION THEREOF

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20250108143A1
SERIAL NO

18841788

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Abstract

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The present invention provides a double-crosslinked fibrin gel, which is a solid hydrogel composed of a network structure with a blocking function and a network structure with an adhesion function, where the network structure with the blocking function is a three-dimensional fibrin network, and the network structure with the adhesion function is a three-dimensional photosensitive gel network; each channel of the photosensitive gel network has a group of the fibrin network inside, and each group of the fibrin network has overall continuity; on the whole, the three-dimensional fibrin network disperses disorderly throughout a surface and an interior of the solid hydrogel. The present invention further provides a raw material composition, a kit for preparing the double-crosslinked fibrin gel, and an application of the kit to prepare an in-situ rapid clotting and hemostatic material. The double-crosslinked fibrin gel prepared by the kit has a fast and efficient hemostatic effect, also can be widely applied for hemostasis of accidental trauma or a surgical wound.

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Patent Owner(s)

Patent OwnerAddress
ZHEJIANG UNIVERSITY310027 NO 38 ZHEJIANG ROAD HANGZHOU ZHEJIANG XIHU DISTRICT HANGZHOU CITY ZHEJIANG PROVINCE 310027

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DING, Yuan Hangzhou, Zhejiang, CN 46 277
MAO, Zhengwei Hangzhou, Zhejiang, CN 3 0
WANG, Weilin Hangzhou, Zhejiang, CN 82 1383
YU, Lisha Hangzhou, Zhejiang, CN 25 419

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