GLYCOENGINEERING OF THERMOTHELOMYCES HETEROTHALLICA

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20250101483A1
SERIAL NO

18833874

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Thermothelomyces heterothallica (formerly Myceliophthora thermophila) genetically modified to produce glycoproteins with N-glycans of mammalian proteins (particularly human, companion animal and other animal proteins) are provided, comprising deletion or disruption of the alg3 gene, expression of ER-targeted Mannosidase 1 (alpha-1.2-Mannosidase), and expression of ER-targeted Glucosidase 2 alpha-subunit. The Th. heterothallica may also further comprise heterologous GlcNAc transferase 1 (GNT1), GlcNAc transferase 2 (GNT2), STT3 subunit of a heterologous oligosaccharyltransferase and galactosyltransferase.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
DYADIC INTERNATIONAL (USA) INC140 INTRACOASTAL POINTE DRIVE SUITE 404 JUPITER FL 33477

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Emalfarb, Mark Aaron Jupiter, US 14 183
Huuskonen, Anne Espoo, FI 23 42
Saloheimo, Markku Espoo, FI 37 78
Tchelet, Ronen Budapest, HU 10 10
Valbuena, Crespo Noelia Seville, ES 7 3

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation