THYROGLOBULIN QUANTITATION BY MASS SPECTROMETRY
Number of patents in Portfolio can not be more than 2000
United States of America
Stats
-
N/A
Issued Date -
Mar 20, 2025
app pub date -
Oct 25, 2024
filing date -
Oct 25, 2024
priority date (Note) -
Published
status (Latency Note)
Importance
Abstract
Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve adding an internal standard to the test sample; digesting thyroglobulin from the test sample and the internal standard to form thyroglobulin peptides; purifying the thyroglobulin peptides; ionizing the thyroglobulin peptides to generate one or more ions detectable by mass spectrometry; quantifying the amount of the one or more ions by mass spectrometry, wherein the one or more ions comprise an ion having a mass/charge ratio of 541.3±0.5, 612.3±0.5, 636.4±0.5, 726.4±0.5, 797.4±0.5, 912.4±0.5, and/or 1059.5±0.5; and relating the amount of the one or more ions to the amount of thyroglobulin in the test sample.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully