ROLLING CIRCLE AMPLIFICATION METHODS AND PROBES FOR IMPROVED SPATIAL ANALYSIS
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United States of America
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Issued Date -
Mar 20, 2025
app pub date -
Sep 17, 2024
filing date -
Sep 17, 2024
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Abstract
The present disclosure relates in some aspects to methods and compositions for analyzing a biological sample. In some aspects, provided herein are probes, methods, and kits for analyzing a processing a biological sample, wherein the processing comprises performing rolling circle amplification of a ribosomal RNA (rRNA)-targeting probe, and detecting a detection probe hybridized to a non-rRNA target analyte (e.g., nucleic acid) in the biological sample.
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