Method for Regulating and Controlling Heterologous Synthetic Flavonoid Compound and Use Thereof

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United States of America

APP PUB NO 20250092431A1
SERIAL NO

18729536

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Abstract

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Provided is a method for synthesizing a flavonoid compound. The method comprises providing a recombinant prokaryotic cell, wherein, in the prokaryotic cell, the transmembrane protein rhodanese Ygap of Escherichia coli is up-regulated or a target gene or target gene combination selected from the following groups is down-regulated: pyrB, accC, accB, purC, glyA, tktA, fabB, leuD, leuC, glpC, folK and leuA. Also provided are a prokaryotic cell for synthesizing a flavonoid compound and the use thereof, and the use of a kit and a regulation and control reagent. The present disclosure achieves significant improvement in the yield of the flavonoid compound.

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Patent Owner(s)

Patent OwnerAddress
CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES300 FENGLIN ROAD XUHUI DISTRICT SHANGHAI 200032

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ji, Dongni Shanghai, CN 1 0
Li, Jianhua Shanghai, CN 146 6005
Wang, Yong Shanghai, CN 1107 9670

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